Magnesium has a profound effect on neural excitability. Symptoms of Mg deficiency are produced by neural and neuromuscular hyperexcitability.These create tetany syndrome (TS). TS symptoms include muscle spasms, cramps and hyperarousal, hyperventilation and asthenia.
Signs and symptoms of TS are frequently encountered in clinical practice, especially among patients with functional or stress-related disorders. The role of Mg deficit in TS is suggested by relatively low levels of serum or erythrocyte Mg.
Mg deficiency increases susceptibility to the physiologic damage produced by stress, and magnesium administration has a protective effect.
In addition, the adrenergic effects of psychological stress induce a shift of Mg from the intracellular to the extracellular space, increasing urinary excretion and eventually depleting body stores.
Leo Galland, Great Smokies Diagnostic Laboratory, Asheville, N.C.,
Magnesium is a natural tranquilizer that calms and nourishes the nervous system.