Friday, October 1, 2010

Inflammation and Magnesium

Inflammation is the missing link to explain the
role of magnesium in many pathological conditions.
Magnesium deficiencies feed the fires of inflammation and pain.

Inflammation is a response from your immune system in response to an irritant. Then, what normally happens, is that our bodies produce proteolytic enzymes which:
counteract the inflammation,
clean the blood,
fight off viral and bacterial infections
break down excess fibrin (scar tissue) that causes the blood to thicken, which sets us up for clots, and can cause a heart attack or stroke
break down fibrosis (scar tissue that builds up in our bodies and over time creates restriction and strain on our organs that they can no longer function properly)
help take some of the strain off of the liver by keeping the blood clean and not allowing it to thicken beyond normal

and things return to normal. After around age 25, our production of these enzymes drops off almost completely so there is nothing to tell the body to stop the inflammation. Most if not all of these enzymes are mediated by magnesium meaning as magnesium levels drop off so do the activities of these crucial biological magnesium sensitive enzymes.

Researchers recognize a silent kind of inflammation. This type of internal inflammation has an insidious nature and is the culprit behind diabetes and heart disease. The continuous low-level stress that silent inflammation places on the body’s defense systems often results in an immune-system breakdown.

Magnesium deficiency causes and underpins chronic inflammatory build ups. Increases in magnesium concentration cause a decrease in the inflammatory response.

Chronically inflamed tissues continue to generate signals that attract leukocytes (white blood cells) from the bloodstream.
When leukocytes migrate from the bloodstream into the tissue they amplify the inflammatory response.

The treatment of chronic inflammation has been problematic for medical science because most of their treatments create more inflammation. Many pain and anti-inflammatory medications are not safe; even over the counter pain medications hold unforeseen dangers. Magnesium chloride safely reduces inflammation and systemic stress because magnesium deficiencies are in great part the cause of both conditions.

It is magnesium that modulates cellular events involved in inflammation.

Inflammation and systemic stress are central attributes of many pathological conditions. In magnesium we have found a potent medicine that is effective across a wide range of pathologies. Instead of different treatments for heart disease, Alzheimer’s and colon cancer, we apply a single, inflammation-reducing remedy that would prevent or treat these and other deadly diseases.

Magnesium acts as a general cell tonic while it reduces inflammation and systemic stress. Equally it is important in overall energy (ATP) production, hormonal and enzyme production and function which all reflect powerfully on the process of inflammation.

Inflammation and Heart disease

Inflammatory reactions in the body are a valuable predictor of impending heart attack. . An American Heart Association paper disclosed that 85% of heart attack victims had gum disease compared to 29% of healthy similar patients.

Inflammation plays a pivotal role in all stages of atherosclerosis, the progressive narrowing and hardening of the arteries over time.

An article in the Journal of the American College of Nutrition showed that as consumption of magnesium fell, the levels of C-reactive protein went up. C-reactive protein, or CRP, is produced in the liver and has emerged as a strong predictor of clinical events of cardiovascular diseases, such as heart attacks and stroke.

Chronic inflammation destabilizes cholesterol deposits in
the coronary arteries, leading to heart attacks and strokes.

Most scientists are showing graphs demonstrating that elevated cholesterol in combination with an elevated C-reactive protein is a better gauge of heart disease risk. It seems that without the inflammation elevated cholesterol is not a threat after all.

Since most heart disease is marked by various levels of inflammation these studies were all highlighting the hidden relationship between inflammation and magnesium deficiency. Its use as an anti inflammatory makes magnesium absolutely indispensable to not only heart patients but also to diabetics, neurological and cancer patients as well.

Inflammation and Metabolic Syndrome

Chronic low-grade inflammation is one of the characteristics of the metabolic syndrome and interferes with insulin physiology.

Ignorance has prevailed over the interrelationship between muscular lipid (fat) accumulation, chronic inflammation and insulin resistance because the central mediating factor is magnesium.

Virtually all the components of the Metabolic Syndrome
of diabetes, high blood pressure, obesity and lipid
disorders are associated with low magnesium.
Dr. Michael R. Eades

A well-timed intervention in the inflammatory process might reverse some, if not all, of the effects of diabetes.

Inflammation, Asthma and allergies

Most allergy and asthma sufferers are familiar with rhinitis (inflammation of the nose), sinusitis (inflammation of the sinuses), and asthma (inflammation of the airways).

Persistent asthma is an inflammatory disease that requires regular anti-inflammatory therapy with magnesium chloride.

Inflammation and Brain diseases

Once we understand the critical importance of
inflammation and glutathione depletion in brain diseases,
we can take steps to prevent or even reverse the damage.
Dr. David Perlmutter

Inflammation and Skin disorders

Inflammation is also behind dermatitis (inflammation of the skin). Magnesium decreases swelling, and, “is effective in the treatment of inflammatory skin diseases.[10]

Inflammation and Depression

Depression also is correlated with inflammation. A study conducted by researchers at the Emory University School of Medicine found that psychological stress leads to an excessive inflammatory response in people. It should come as no surprise that magnesium supplementation has a great effect on depression.

In the final analysis there is no single medicine or nutritional agent (like magnesium), that has the power to both treat and prevent chronic inflammatory conditions.

Extracted from

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