Magnesium is the premier medicine for depression, sleep disturbances, emotionally disturbed behavior, and neurological diseases because of its strong positive effect in calming and nourishing the nervous system.
It is essential in regulating central nervous system excitability thus a deficiency may cause aggressive behavior, depression, or suicide. Observational and experimental studies have shown an association between magnesium and aggression, anxiety, ADHD, bipolar disorder, depression and schizophrenia.
Magnesium permits calcium to enter a nerve cell to allow electrical
transmission along the nerves to and from the brain. Even our
thoughts, via brain neurons, are dependent on magnesium.
Dr. Carolyn Dean
transmission along the nerves to and from the brain. Even our
thoughts, via brain neurons, are dependent on magnesium.
Dr. Carolyn Dean
ADHD
The Department of Family Medicine, Pomeranian Medical Academy, states that dietetic factors can play a significant role in the origin of ADHD and that magnesium deficiency can result in disruptive behaviors.
Even a mild deficiency of magnesium can cause sensitiveness to noise, nervousness, irritability, mental depression, confusion, twitching, trembling, apprehension, and insomnia.
(The effects of magnesium physiological supplementation on hyperactivity in children with ADHD. Mag Res 1997; 10(2):149-56.)
Magnesium deficiency measured in 95% of 116 Polish children with ADHD: 78% low hair, 59% low RBC’s, 34% low serum.
(Magnesium Research 10(2): 143-148 1997)
In another study, just 200mg of elemental magnesium given to hyperactive children produced a noticeable decrease in hyperactivity over a 6 month period.
(Magnesium Research 10(2): 149-156 1997)
Several studies have shown a connection between magnesium and ADHD.
1.Durlach J. Clinical aspects of chronic magnesium deficiency, in MS Seelig, Ed. Magnesium in Health and Disease. New York, Spectrum Publications, 1980.
2.Kozielec T, Starobrat-Hermelin B. Assessment of magnesium levels in children with attention deficit hyperactivity disorder (ADHD). Magnes Res 10(2):143-8, 1997.
3.Kozielec T, Starobrat-Hermelin B. Assessment of magnesium levels in children with attention deficit hyperactivity disorder (ADHD). Magnes Res 10(2):143-8, 1997.
4.Starobrat-Hermelin B, Kozielec T. The effects of magnesium physiological supplementation on hyperactivity in children with attention deficit hyperactivity disorder (ADHD). Positive response to magnesium oral loading test. Magnes Res 10(2):149-56, 1997.
Aggression
Magnesium is essential in regulating central nervous system excitability thus magnesium-deficiency may cause aggressive behavior
Observational and experimental studies have shown an association between magnesium and aggression.
[6] Izenwasser SE et al. Stimulant-like effects of magnesium on aggression in mice. Pharmacol Biochem Behav 25(6):1195-9, 1986.
[7] Henrotte JG. Type A behavior and magnesium metabolism. Magnesium 5:201-10, 1986.
[8] Bennett CPW, McEwen LM, McEwen HC, Rose EL. The Shipley Project: treating food allergy to prevent criminal behaviour in community settings. J Nutr Environ Med 8:77-83, 1998.
[9] Kirow GK, Birch NJ, Steadman P, Ramsey RG. Plasma magnesium levels in a population of psychiatric patients: correlation with symptoms. Neuropsychobiology 30(2-3):73-8, 1994.
[10] Kantak KM. Magnesium deficiency alters aggressive behavior and catecholamine function. Behav Neurosci 102(2):304-11, 1988
Alzheimer’s disease
Dr. Jean Durlach, of Hôpital Saint-Vincent-de-Paul in France, recognized fifteen years ago the importance of magnesium in the development of Alzheimer’s
(Magnesium Research (1990) 3, 3, 217-218)
“Numerous studies have revealed the increased presence of aluminum (Al) in brain tissue obtained from autopsies of Alzheimer disease patients.” – Dr Jean Durlach
“Mg values are found to be significantly decreased in brain regions of diseased patients compared to the controls” - Dr. E Andrasi
(Andrasi E, Igaz S, Molnar Z, Mako S. Disturbances of magnesium concentrations in various brain areas in Alzheimer's disease. L. Eotvos University, Budapest, Hungary. Magnes Res. 2000 Sep;13 (3):189-96)
Dr. J.L. Glick in 1990 showed a significant decrease in the frequency of intracellular magnesium deposits in neurons of Alzheimer disease patients as compared with control patients (Dementias: the role of magnesium deficiency and an hypothesis concerning the pathogenesis of Alzheimer's disease. Med. Hypotheses 31, 211-225.)
Magnesium calms the brain and people do not need to become severely deficient in magnesium for the brain to become hyperactive. One study confirmed earlier reports that a marginal magnesium intake overexcites the brain's neurons and results in less coherence--creating cacophony rather than symphony—according to (EEG) measurements. (http://www.ars.usda.gov/is/np/fnrb/fnrb1095.htm#calm)
In an article recently published in the Journal of Orthomolecular Medicine, a study involving 668 autopsy-verified Alzheimer's brains, showed an increased risk by a factor of 2.5 in people drinking water with more than 100 micrograms of aluminium.
"The reason (contact with aluminium) does not cause Alzheimer's in everybody is that its toxicity varies with people's intake of things like calcium and magnesium," says Foster. Aluminium ingestion is bad news for those who are deficient in these two minerals.
"Another thing that is making it much worse is that in processing food, we tend to take out a lot of the magnesium, so that fast foods and processed white bread are much lower in magnesium than (food) our ancestors would get."
Anxiety
Observational and experimental studies have shown an association between magnesium and anxiety.
Buist RA. Anxiety neurosis: The lactate connection. Int Clin Nutr Rev 5:1-4, 1985.
Seelig MS, Berger AR, Spieholz N. Latent tetany and anxiety, marginal Mg deficit, and normocalcemia. Dis Nerv Syst 36:461-5, 1975.
Durlach J, Durlach V, Bac P, et al. Magnesium and therapeutics. Magnes Res 7(3/4):313-28, 1994.
Bipolar Disorder
Observational and experimental studies have shown an association between magnesium and bipolar disorder.
[18] George MS, Rosenstein D, Rubinow DR, et al. CSF magnesium in affective disorder: lack of correlation with clinical course of treatment. Psychiatry Res 51(2):139-46, 1994.
[19] Kirov GK, Birch NJ, Steadman P, Ramsey RG. Plasma magnesium levels in a population of psychiatric patients: correlations with symptoms. Neuropsychobiology 1994;30(2-3):73-8, 1994.
Depression
Observational and experimental studies have shown an association between magnesium and depression.
[20] Linder J et al. Calcium and magnesium concentrations in affective disorder: Difference between plasma and serum in relation to symptoms. Acta Psychiatr Scand 80:527-37, 1989
[21] Frazer A et al. Plasma and erythrocyte electrolytes in affective disorders. J Affect Disord 5(2):103-13, 1983.
[22] Bjorum N. Electrolytes in blood in endogenous depression. Acta Psychiatr Scand 48:59-68, 1972.
[23] Cade JFJA. A significant elevation of plasma magnesium levels in schizophrenia and depressive states. Med J Aust 1:195-6, 1964.
Emotions
Chocolate cravings are potentially a sign of a magnesium deficiency since chocolate is high in magnesium. The mood changing effect is greater when magnesium is used medicinally in high doses, which is most efficiently administered transdermally. Natural magnesium chloride (magnesium oil) is more effective to raise cellular magnesium levels to affect moods positively.
Epilepsy
In a trial with 30 epileptics 450 mg of magnesium supplied daily successfully controlled seizures.
Another study found that the lower the magnesium blood levels the more severe was the epilepsy. In most cases magnesium works best in combination with vitamin B6 and zinc.
Learning disorders
It is probable that low total body magnesium contributes to heavy metal toxicity in children and is a participant in the etiology of learning disorders.
“Magnesium deficiency in children is characterized by excessive fidgeting, anxious restlessness, psychomotor instability and learning difficulties in the presence of normal IQ,” said Dr. Mildred Seelig.
Pupils with mental handicap should be provided with
magnesium preparations because their effects are highly positive.
http://www.autism.org/vitb6.html
magnesium preparations because their effects are highly positive.
http://www.autism.org/vitb6.html
Parkinson’s and Multiple Sclerosis
Evidence is mounting that low levels of magnesium contribute to the heavy metal deposition in the brain that precedes Parkinson’s, multiple sclerosis and Alzheimer’s.
Many of the symptoms of Parkinson’s disease can be overcome with high magnesium supplementation.
Symptoms that multiple sclerosis (MS) has in common with magnesium deficiency include muscle spasms, weakness, twitching, muscle atrophy, incontinence, nystagmus (rapid eye movements), hearing loss, and osteoporosis.
Symptoms that multiple sclerosis (MS) has in common with magnesium deficiency include muscle spasms, weakness, twitching, muscle atrophy, incontinence, nystagmus (rapid eye movements), hearing loss, and osteoporosis.
People with MS also have higher rates of epilepsy than controls, which have been linked to magnesium deficiencies.
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