Evidence is mounting that low levels of magnesium contribute to the heavy metal deposition in the brain that precedes Alzheimer’s.
Mg values are found to be significantly decreased in brain regions of (Alzheimer’s) patients compared to the controls. Dr. E Andrasi
Andrasi E, Igaz S, Molnar Z, Mako S. Disturbances of magnesium concentrations in various brain areas in Alzheimer's disease. L. Eotvos University, Budapest, Hungary. Magnes Res. 2000 Sep;13 (3):189-96.
Dr. J.L. Glick in 1990 showed a significant decrease in the frequency of intracellular magnesium deposits in neurons of Alzheimer disease patients as compared with control patients
Normalizing brain levels of magnesium may help fight deposition of aggregated beta-amyloid (Abeta) as seen in Alzheimer’s disease and related dementias
Evidence is presented indicating that dementias are associated with a relative insufficiency of Magnesium (Mg) in the brain.
Med Hypotheses 1990 Dec;33(4):preceding 301.
Our data suggest that there is a relationship between serum Mg levels and the degree of Alzheimer’s disease and that the determination of the Mg level at various stages may provide valuable information in further understanding the progression and treatment of Alzheimer’s disease.
Undoubtedly the trigger mechanism of Altzheimer’s is the accumulation of heavy metals in the nervous system causing free radical damage leading to DNA and Mitochondrial DNA (mtDNA) damage.
Mercury:
In a human autopsy study, brain tissues from people with AD at death were compared with an age-matched group of control brains from subjects without AD. Mercury content was considerably higher in the AD group. Mercury concentration was prominent in the brain structures involved in memory function.
Many researchers feel that the actual cause of Alzheimer’s disease is due to toxic metal that leaches from mercury-silver amalgam dental fillings. Mercury vapor from amalgam fillings is absorbed into the sinuses and goes through the blood stream directly to the brain.
Vaccines as well as the air, water and food we eat all contain mercury.
Aluminum:
Is neurotoxic even in minute quantities. Normally, the brain is protected form toxic substances by a membrane, the blood-brain barrier. However, because aluminum seems to be concentrated in brain tissue of Alzheimer's victims, it is assumed that there must be a defect in the barrier system permitting aluminum to enter.
Dr. Jean Durlach recognized fifteen years ago the importance of magnesium in the development of Alzheimer’s saying. “Numerous studies have revealed the increased presence of aluminum (Al) in brain tissue obtained from autopsies of Alzheimer disease patients.”
Mg depletion, particularly in the hippocampus, appears to represent an important pathogenic factor in Alzheimer's disease. It is associated with high aluminum incorporation into brain neurons - Dr.Jean Durlach
Dr. Glick suggests that Alzheimer's disease involves a defective transport process characterized by both an abnormally low Mg incorporation and an abnormally high Al incorporation into brain neurons.
Aluminum given to a healthy subject will bring on symptoms of tremors, forgetfulness, disorientation, a very dry, or weeping eczema and skin rashes, as well as other nerve and brain tissue disorders.
Magnesium protects cells from aluminium ,mercury, lead, cadmium, beryllium and nickel. Low magnesium is associated with glutathione depletion. This is vital since glutathione is one of the few antioxidant molecules known to neutralize mercury.
In an article recently published in the Journal of Orthomolecular Medicine, an Ontario study involving 668 autopsy-verified Alzheimer's brains, showed an increased risk by a factor of 2.5 in people drinking water with more than 100 micrograms of aluminium. Blood brain barrier permeability:
The integrity and function of the BBB is critical for overall brain function. Changes in permeability often reflect alterations in BBB transport systems. Causes of generalized changes in BBB permeability include organic solvents, enzymes, heavy metals and free radicals.
Magnesium has an important role at the BBB and is the crucial nutrient that makes a big difference in prevention and treatment of Alzheimer’s disease
More benefits of Magnesium
Memory and the overall functioning of our brains depend on proteins in our brains called NMDA receptors, which allow our neurons to communicate with each other.
An understanding of the strategic importance of magnesium at these crucial NMDA receptor sites confirms the medical view that heavy magnesium supplementation would lead to better treatments for schizophrenia, Alzheimer’s disease, and stroke.
Magnesium permits calcium to enter a nerve cell to allow electrical transmission along the nerves to and from the brain. Even our thoughts, via brain neurons, are dependent on magnesium.
Dr. Carolyn Dean
Magnesium is essential in regulating central nervous system excitability. It calms the brain and people do not need to become severely deficient in magnesium for the brain to become hyperactive.
One study confirmed earlier reports that a marginal magnesium intake overexcites the brain's neurons and results in less coherence--creating cacophony rather than symphony--according to (EEG) measurements.
Of all the macronutrient minerals in the human body,
magnesium is the one most likely to be deficient.
Even a mild deficiency of magnesium can cause sensitiveness to noise, nervousness, irritability, mental depression, confusion, twitching, trembling, apprehension, and insomnia.
The two most basic requirements for the normal operation of our brain are a sufficient energy supply and an optimal presence of biochemicals involved in transmitting messages. Magnesium is crucial in both the production of energy and neurotransmitters and the integrity of the blood brain barrier. It is solid science that connects magnesium to neurological disorders.